2008年获山东大学博士学位；
2009年5月至2011年9月，中国科学院微生物研究所博士后流动站；
2011年9月到中国农业科学院生物技术研究所工作。

主要研究领域为：1、毕赤酵母代谢调控机制 ;2、微生物高效表达系统挖掘及应用 。曾主持一项国家自然科学基金项目（冷休克蛋白调控腾冲嗜热厌氧杆菌冷应激反应的机制《32100072》）、参加十二五863 课题（基因组多位点快速进化与改良《2012AA022105》）和国家自然科学基金项目《链霉菌次级代谢产物生物合成中重要调控基因作用的分子机制》。主持国家自然基金面上项目（食品级毕赤酵母鼠李糖诱导系统高效表达机制的研究《31671802》）（2016-2020）

代表性成果：

1. Bo Liu, Yuwei Zhang, Xue Zhang, Chengliang Yan, Yuhong Zhang, Xinxin Xu, Wei Zhang. Discovery of a rhamnose utilization pathway and rhamnose-inducible promoters in Pichia pastoris . Scientific Reports, 2016, 6: 27352.

2. Wang Chuan, Jin Chunlei, Zhang Jihui, Bao Qiyu, Liu Bo*, Huarong Tan*. Transcriptomic analysis of Thermoanaerobacter tengcongensis grown at different temperatures by RNA sequencing. Journal of Genetics and Genomics, 2015, DOI: 10.1016/j.jgg.2015.03.005. ( *, Corresponding author ).

3. Liu Bo, Zhang Yuhong, Zhang Wei. RNA-Seq-based analysis of cold shock response in Thermoanaerobacter tengcongensis , a bacterium harboring a single cold shock protein encoding gene. PLoS One. 2014, 9(3): e93289.

4. Nie Chunming^#, Liu Bo^#, Zhang Yuhong, Zhao Guofen, Fan Xiaohu, Ning Xiaoyan, Zhang Wei. Production and secretion of Lactobacillus crispatus beta-galactosidase in Pichia pastoris . Protein Expression and Purification, 2013, 92, 88-92. (#, Co-first Author)

6. Liu Bo, Wang Chuan, Yang Haihua, Tan Huarong. Establishment of a genetic transformation system and its application in Thermoanaerobacter tengcongensis . Journal of Genetics and Genomics, 2012, 39: 561-570.

7. Zhang Shuli^#, Liu Bo^#, Yang Haihua, Tian Yuqing, Liu Gang, Li Lei, Tan Huarong. Characterization of EndoTT, a novel single-stranded DNA specific endonuclease from Thermoanaerobacter tengcongensis . Nucleic Acids Research, 2010, 38: 3709–3720. (^#, Co-first author)