梁成真博士、研究员、博士生导师

博士
研究员
博士生导师

liangchengzhen@caas.cn
研究中心

作物分子生物学

创新团队

作物生物技术育种

课 题 组

张锐课题组

招生方向

生物化学与分子生物学

学习工作经历

2006年7月在西北农林科技大学获学士学位;
2009年7月在中国农科院生物技术研究所获硕士学位;br>2014年7月在中科院遗传与发育生物学研究所获博士学位;
2015年12月 - 2017年12月任中国农科院生物技术研究所助理研究员;
2018年1月 - 2020年12月任中国农科院生物技术研究所副研究员;
2021年1月 - 至今任中国农科院生物技术研究所研究员.
社会兼职:中国农业生物化学与分子生物学会青委会委员

主要研究领域与成果

主要开展棉花三系育性分子基础和抗性育种应用研究。主持国家高层次人才计划项目,国家自然科学基金面上项目、青年项目,转基因重大专项(任务)等课题6项。在PNAS、Mol Plant、New phytol、Plant Biotechnol J等国际学术期刊发表SCI论文32篇,获授权发明专利12项。获亚洲青年棉花科学家奖、“树兰”优秀青年论文一等奖、“振声”优秀博士生奖、“朱李月华”优秀博士生奖。

主要研究领域与成果

主要从事棉花三系育性的分子基础和纤维形成的遗传机制研究。

2021年

1.Zhang J#,*, Liu S, Liu B, Wang X, Yao J, Zhai M, Liu B, Liang C*, Shi H* (2021) Highly efficient Ti3+ self-doped TiO2 co-modified with carbon dots and palladium nanocomposites for disinfection of bacterial and fungi. J Hazard Mater.413:125348. (IF:10.59)

2.Wang Y#, Wang Y#, Meng Z, Wei Y, Du X*, Liang C*, Zhang R* (2021) Elevation of GhDREB1B transcription by a copy number variant significantly improves chilling tolerance in cotton. Planta. 254:42. (IF:4.12)

2020年

3.Ji G#, Liang C#, Cai Y#, Pan Z, Meng Z, Li Y, Jia Y, Miao Y, Pei X, Gong W, Wang X, Gao Q, Peng Z, Wang L, Sun J, Geng X, Wang P, Chen B, Wang P, Zhu T, He S*, Zhang R*, Du X* (2020) A copy number variant at the HPDA-D12 locus confers compact plant architecture in cotton. New Phytol. 229: 2091-2103. (IF:10.15)

4.Wang Y#, Liang C#, Wu S, Jian G, Zhang X, Zhang H, Tang J, Li J, Jiao G, Li F, Chu C* (2020) Vascular-specific expression of Gastrodia antifungal protein gene significantly enhanced cotton Verticillium wilt resistance. Plant Biotechnol J. 18: 1498-1500. (IF:9.80)

5.Syed T#, Askari M#, Meng Z, Li Y, Ali Abid M, Wei Y, Guo S, Liang C*, Zhang R* (2020) Current insights on vegetative insecticidal proteins (Vip) as next generation pest killers. Toxins. 12: 522. (IF:4.55)

6.Li Y#, Guo L#, Liang C, Meng Z, Syed T, Guo S, Zhang R* (2020) Overexpression of Brassica napus cytosolic fructose-1,6-bisphosphatase and sedoheptulose-1,7-bisphos-phatase genes significantly enhanced tobacco growth and biomass. J Integr Agr. 19: 2-12. (IF:2.85)

7.Muhammad A #, Wang P#, Zhu T, Liang C, Meng Z, Malik W, Guo S, Zhang R* (2020) Construction of Gossypium barbadense mutant library provides genetic resources for cotton germplasm improvement. Inter J Mol Sci. 21: 6505. (IF:5.92)

8.Akram U#, Song Y#, Liang C, Muhammad A, Askari M, Myat A, Abbas M, Malik W, Ali Z, Guo S, Zhang R, Meng Z* (2020) Genome-wide characterization and expression analysis of NHX gene family under salinity stress in Gossypium barbadense and its comparison with Gossypium hirsutum. Genes. 11: 803. (IF:4.10)

9.Razzaq A#, Ashraf J, Malik W*, Shaban M, Zhang R, Liang C, Hanif M, Ali Abid M, Qayyum A (2020) In silico analyses of TALE transcription factors revealed its potential role for organ development and abiotic stress tolerance in cotton. Inter J Agr Biol. 23: 1094.

2019年

10.Zhang J#,*, Wang X, Suo X, Liu X, Liu B, Yuan M, Wang G, Liang C*, Shi H* (2019) Cellular response of Escherichia coli to photocatalysis: Flagellar assembly variation and beyond. ACS NANO.13:2004-2014. (IF:14.59)

11.Wang Y#, Liang C#, Meng Z, Li Y, Abid A, Askari M, Wang P, Wang Y, Sun G, Cai Y, Chen SY, Lin Y*, Zhang R*, Guo S* (2019) Leveraging Atriplex hortensis choline monooxygenase to improve chilling tolerance in cotton. Environ Exp Bot. 162: 364-373. (IF:4.03)

12.李霞,范鑫,梁成真,王远,张锐,孟志刚,刘晓东,孙国清 (2019) BS2基因在烟草中的功能解析. 中国农业科技导报. 21: 43-50.

13.王裴林, 周利利, 梁成真, 孟志刚,郭三堆,张锐 (2019) 棉花线粒体基因cRT-PCR改良及其在寻找CMS相关基因中的应用. 生物技术进展. 9: 303-308.

2018年

14.He D#, Zhao X#, Liang C#, Zhu T, Abid A, Cai Y, He J*, Zhang R* (2018) Genetic variation in LBL1contributes to depth of leaf blades lobes between two cotton subspecies, Gossypium barbadense and Gossypium hirsutum. J Integr Agr. 17: 2394-2404. (IF:1.34)

15.Waqas M, Muhammad SAS, Muhammad AA, Ghulam Q, Etrat N, Abdul Q, Liang C, Guo S, Zhang R (2018) Genetic basis of variation for fiber quality and quality related biochemical traits in Bt and non-Bt colored cotton. Int J Agric Biol. 20(9):2117-2124. (IF:0.87)

16.Abid A, Liang C, Malik W, Meng Z, Zhu T, Meng Z, Ashraf J, Guo S, Zhang R (2018) Cascades of ionic and molecular networks involved in expression of genes underpin salinity tolerance in cotton. J Plant Growth Regul. 37: 668-679. (IF:2.18)

17.范鑫, 赵雷霖, 翟红红, 王远, 孟志刚, 梁成真, 张锐, 郭三堆, 孙国清. (2018) AtNEK6在棉花旱盐胁迫响应中的功能分析. 中国农业科学. 51:4230-4240.

18.杨羊, 梁成真, 孟志刚, 陈全家, 罗淑萍, 张锐, 郭三堆 (2018) 基于GR79 EPSPS筛选标记的抗虫抗除草剂表达载体构建及抗性鉴定. 中国农业科技导报. 20: 22-28.

2017年

19.Liang C#, Sun B#, Meng Z, Meng Z, Wang Y, Sun G, Zhu T, Lu W, Zhang W, Malik W, Lin M*, Zhang R*, and Guo S* (2017). Co-expression of GR79 EPSPS and GAT yields herbicide-resistant cotton with low glyphosate residues. Plant Biotechnol J. 15: 1622-1629. (IF:6.31)

20.Liang C#, Liu Y#, Li Y#, Meng Z, Zhu T, Wang Y, Kang S, Abid A, Malik W, Sun G, Guo S*, and Zhang R* (2017) Activation of ABA receptors gene GhPYL9-11A is positively correlated with cotton drought tolerance in transgenic Arabidopsis. Front Plant Sci. 8: 1453. (IF:3.69)

21.Liang C#, Li A#, Yu H#, Li W, Liang C, Guo S, Zhang R*, and Chu C* (2017) Melatonin regulates root architecture by modulation auxin response in rice. Front Plant Sci. 8: 134. (IF:3.69)

22.Wang Y#, Meng Z#, Liang C#, Meng Z, Wang Y, Sun G, Zhu T, Cai Y, Guo S*, Zhang R*, and Lin Y* (2017) Increased lateral root formation by CRISPR/Cas9-mediated editing of arginase genes in cotton. SCIENCE CHINA Life Sci. 5: 524-527. (IF:3.09)

23.Zhu T, Liang C, Meng Z, Sun G, Meng Z, Guo S, Zhang R* (2017) CottonFGD: an integrated functional genomics database for cotton. BMC Plant Biol. 17: 101. (IF:3.93)

24.Zhu T, Liang C, Meng Z, Guo S, Zhang R* (2017) GFFsort: An efficient tool to sort GFF3 files for tabix indexing. BMC Bioinformatics. 18: 482. (IF:2.45)

25.赵雷霖, 范鑫, 聂星, 梁成真, 张锐, 孙国清, 孟志刚, 林敏, 王远, 郭三堆 (2017) 异源表达irrE转基因烟草的耐盐耐旱性. 中国农业科学. 50: 3860-3870.

26.李琴, 陈全家, 孟志刚, 张锐, 梁成真, 孙国清, 孟钊红, 翟红红, 张杰, 郭三堆 (2017) cry2Ah-M基因杀虫活性研究. 中国农业科技导报. 19: 10-16.

27.王艳玲, 孟志刚, 李妍妍, 孟钊红, 王远, 孙国清, 朱涛, 梁成真, 蔡永萍, 郭三堆, 张锐, 林毅 (2017) CRISPR/Cas9编辑棉花精氨酸酶基因促进侧根形成和发育. 中国科学:生命科学. 47: 1-4.

2016年

28.Wang Y#, Liang C#, Wu S#, Zhang X#, Tang J, Jian G, Jiao G*, Li F*, Chu C* (2016) Significant improvement of cotton Verticillum Wilt resistance by manipulation the expression of Gastrodia antifungal proteins. Mol Plant. 9:1436-1439. (IF:8.83)

29.Liang C#, Meng Z, Meng Z, Malik W, Yan R, Lwin KM, Lin F, Wang Y, Sun G, Zhou T, Zhu T, Li J, Jin S, Guo S*, Zhang R* (2016). GhABF2, a bZIP transcription factor, confers drought and salinity tolerance in cotton (Gossypium Hirsutum L.). Sci Rep. 6, pp.35040. (IF:4.26)

30.Yan R#, Liang C#, Meng Z, Malik W, Zhu T, Zong X, Guo S*, Zhang R* (2016) Progress in genome sequencing will accelerate molecular breeding in cotton (Gossypium spp.). 3 Biotech. 6:217. (IF:1.36)

31.Abid M, Malik W, Yasmeed A, Qayyum A, Zhang R, Liang C, Guo S, Ashraf J (2016) Mode of inheritance for biochemical traits in genetically engineered cotton under water stress. AoB Plants. 8: plw008. (IF:2.24)

32.Sun G, Zhang D, Zhang R, Wang Y, Meng Z, Zhou T, Liang C, Zhu T (2016) Bt protein expression in the transgenic insect-resistant cotton in China. Sci Bull. 61: 1555-1557 (IF:4.00)

2015年

33.Liang C#, Zheng G, Li W, Wang Y, Hu B, Wang H, Wu H, Qian Y, Zhu XG, Tan DX, Chen SY, Chu C* (2015) Melatonin delays leaf senescence and enhances salt stress tolerance in rice. J Pineal Res. 59: 91-101. (IF:9.34)

34.Liang C# and Chu C* (2015) Towards understanding abscisic acid-mediated leaf senescence. SCIENCE CHINA Life Sci. 58(5): 506-508. (IF:2.30)

35.Hu B, Wang W, Ou S, Tang J, Li H, Che R, Zhang Z, Chai X, Wang H, Wang Y, Liang C, Liu L, Piao Z, Deng Q, Deng K, Xu C, Liang Y, Zhang L, Li L, Chu C* (2015) Variation in NRT1.1B contributes to nitrate-use divergence between rice subspecies. Nat Genet. 47(7): 834-838. (IF:31.62)

36.Liu L, Tong H, Xiao Y, Che R, Xu F, Hu B, Liang C, Chu J, Li J*, Chu C* (2015) Activation of Big Grain1 significantly improves grain size by regulating auxin transport in rice. Proc. Natl. Acad. Sci. USA. 112(35): 11102-11107. (IF:9.42)

37.Meng Z, Meng Z, Zhang R, Liang C, Wan J, Wang Y, Zhai H, Guo S* (2015) Expression of the rice arginase gene OsARG in cotton influences the morphology and nitrogen transition of seedlings. PloS One. 11: e0141530 (IF:2.81)

2014年

38.Liang C#, Wang Y#, Zhu Y, Tang J, Hu B, Liu L, Ou S, Wu H, Chu C* (2014) OsNAP connects abscisic acid and leaf senescence by fine-tuning abscisic acid biosynthesis and directly targeting senescence-associated genes in rice. Proc. Natl. Acad. Sci. USA. 111:10013-10018. (IF:9.67)

2014年之前

39.Wang H, Fang J, Liang C, He M, Li Q, Chu C (2011) Computation-assisted SiteFinding-PCR for isolating flanking sequence tags in rice. BioTechniques. 51: 421-423. (IF:2.30)

40.梁成真, 张锐, 孙国清, 孟志刚, 周焘, 丁中涛, 郭三堆 (2010) 优化TAIL-PCR方法克隆棉花抗逆相关转录因子编码基因. 棉花学报. 22(3): 195-201.

41.梁成真, 张锐, 郭三堆 (2009) 染色体步移技术研究进展. 生物技术通报. 10: 75-87.

42.张晓, 张锐, 孙国清, 史计, 孟志刚, 周焘, 侯思宇, 梁成真, 于源华, 郭三堆 (2012) 优化的反向PCR结合TAIL-PCR法克隆棉花线粒体atpA双拷贝基因及其侧翼序列. 生物工程学报. 28: 104-115.