2019.1～至今 中国农业科学院生物技术研究所 副研究员

2016.8～2018. 12 中国农业科学院生物技术研究所 助理研究员

2014.1～2016.7 中国农业科学院生物技术研究所 博士后

2007.9～2014.1 中国科学院大学 遗传学 硕博连读

2003.9～2007.6 山东师范大学 生物科学 本科

主要从事农作物秸秆的高值转化利用和微生物智能细胞工厂构建等研究。开发了利用秸秆高效生物合成人造淀粉和单细胞蛋白的生物炼制新技术，建立了工业酶丝状真菌表达平台。以第一或通讯作者在Sci. Bull.、Biotechnol. Biofuels和Microb. Cell. Fact.等国际知名期刊发表SCI论文14篇，授权发明专利16项，主持国家重点研发计划青年科学家项目、国家自然科学基金面上及青年项目、国家重点研发计划子课题等7项。研发的多种酶制剂与企业签订技术转让/开发合同4项，累计到账金额420万元。

发表论文：

1.Xu Xinxin, Zhang Wei, You Chun, Fan Chao, Ji Wangli, Park Jong-Tae, Kwak Jiyun, Chen, Hongge, Zhang Yi-Heng, Ma Yanhe. Biosynthesis of artificial starch and microbial protein from agricultural residue. Sci Bull 2023, 68 (2): 214-223.

2.Ji Wangli, Wang Xiaolu, Liu Xiaoqing, Wang Yuan, Liu Fangui, Xu Bo, Luo Huiying, Tu Tao, Zhang Wei, Xu Xinxin*, Su Xiaoyun*. Combining manipulation of integration loci and secretory pathway on expression of an Aspergillus niger glucose oxidase gene in Trichoderma reesei. Microb Cell Fact 2023, 22 (1): 38.

3.Fan Chao, Zhang Wei, Su Xiaoyun, Ji Wangli, Luo Huiying, Zhang Yuhong, Liu Bo, Yao Bin, Huang Huoqing*, Xu Xinxin*. CRISPR/Cas9-mediated genome editing directed by a 5S rRNA-tRNAGly hybrid promoter in the thermophilic filamentous fungus Humicola insolens. Biotechnol Biofuels 2021, 14 (1): 206.

4.Xu Xinxin, Fan Chao, Song Liya, Li Jinyang, Chen Yuan, Zhang Yuhong, Liu Bo, Zhang Wei. A novel CreA-mediated regulation mechanism of cellulase expression in the thermophilic fungus Humicola insolens. Int J Mol Sci, 2019, 20 (15): 3693

5.Xu Xinxin, Fan Xiaohu, Fan Chao, Qin Xing, Liu Bo, Nie Chunming, Sun Ning, Yao  Qingzhi, Zhang Yuhong, Zhang Wei. Production optimization of an active β-galactosidase of Bifidobacterium animalis in heterologous expression systems. BioMed Res Int, 2019, 2019: 8010635 第一作者 (IF: 2.276)

6.Yan Chengliang ^#, Xu Xinxin^#, Zhang Xue, ZhangYuwei, Zhang Yuhong, Zhang Zhifang , Zhang Wei*, Liu Bo*. Decreased rhamnose metabolic flux improved production of target proteins and cell flocculation in Pichia pastoris. Frontiers in Microbiology. 2018, 9:1771.

7.Ning Xiaoyan , Zhang Yanli , Yuan Tiantian , Li Qingbin , Tian Jian , Guan Weishi , Liu Bo , Zhang Wei , Xu Xinxin^*, Zhang Yuhong^*. Enhanced thermostability of glucose oxidase through computer-Aided molecular design. Int. J. Mol. Sci. 2018,19, 425.

8.Fan Chao^#, Xu Xinxin^#, Song Liya, Guan Weishi, Li Jinyang , Liu Bo, Shi Pengjun, Zhang Wei. The use of Agrobacterium-mediated insertional mutagenesis sequencing to identify novel genes of Humicola insolens involved in cellulase production, 3 Biotech .2018, 8: 153.

9.Xia Wei^#, Xu Xinxin^#, Qian Liqun , Shi Pengjun*, Bai Yingguo, Luo Huiying, Ma Rui, Yao Bin*. Engineering a highly active thermophilic β-glucosidase to enhance its pH stability and saccharification performance, Biotechnol Biofuels, 2016, 9:147.

10.Xu Xinxin, Li Jinyang, Shi Pengjun, Ji Wangli, Liu Bo, Zhang Yuhong, Yao Bin, Fan Yunliu, Zhang Wei. The use of T-DNA insertional mutagenesis to improve cellulase production by the thermophilic fungus Humicola insolens Y1，Scientific Reports，2016.8.10.

11.Li Jinyang^#，Xu Xinxin^#，Shi Pengjun，Liu Bo , Zhang Yuhong, Zhang Wei. Overexpression and characterization of a novel endo-β-1,3(4) -glucanase from thermophilic fungus Humicola insolens Y1，Protein Expres Purif，2017.138.63-68.

12.徐欣欣，张伟，刘波等，根瘤农杆菌介导的特异腐质霉的遗传转化方法及其表达载体，ZL 201610582793.1，发明专利

13.徐欣欣，张伟，刘波等. 调控真菌木质纤维素降解酶系表达的元件及其应用，ZL202010708586.2，发明专利